Protein Science Group Manager
- This job was published on May 2, 2024
- Start date - Now
- End date - Without end
- Location - USA
- Full-Time
Responsibilities
- Lead and manage the protein production team, providing mentorship and technical guidance.
- Oversee recombinant protein expression in bacterial, mammalian, insect, or yeast systems.
- Develop, optimize, and scale up protein purification strategies (e.g., affinity, ion exchange, size exclusion chromatography).
- Ensure quality control of produced proteins using techniques such as SDS-PAGE, Western blotting, SEC-MALS, and mass spectrometry.
- Troubleshoot protein expression and purification challenges, implementing solutions to improve yield and purity.
- Manage production timelines and resources to meet project deadlines efficiently.
- Maintain compliance with industry standards, regulatory guidelines, and safety protocols.
- Oversee documentation, SOPs, and batch records for all production activities.
Qualifications
- Ph.D. in Biochemistry, Molecular Biology, Biotechnology, or a related field.
- 5+ years of experience in protein expression and purification, with at least 2 years in leadership role.
- Expertise in recombinant protein production using bacterial, mammalian, yeast, or insect cell systems.
- Hands-on experience with chromatography techniques (e.g., AKTA systems) and analytical characterization.
- Strong troubleshooting skills for protein aggregation, solubility, and stability issues.
- Knowledge of protein structure by NMR, X-ray and CryoEM (a plus).
- Excellent leadership, project management, and communication skills.
- Experience in a GMP or regulated environment (preferred but not required).
Why Join Us?
Opportunity to work in a cutting-edge scientific environment.
Collaborative and innovative company culture.
Competitive salary, benefits, and career development opportunities.
Benefits
401(k)
Health insurance
Dental insurance
Disability insurance
Family leave
Paid time off
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Apply for: Protein Science Group Manager
- Start date - Now
- End date - Without end
- Location - USA
- Full-Time